MAGED1 Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51582m |
| Product Name | MAGED1 Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | KLH conjugated synthetic peptide derived from human MAGED1 |
| Immunogen Range | 50-200/778 |
| Clonality | Monoclonal |
| Clone # | C5D3 |
| Concentration | Lot Dependent |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 9500 |
| Swiss Prot | Q9Y5V3 |
| Subcellular location | Cytoplasm, Nucleus, Cell membrane |
| Synonyms | DLXIN 1; MAGD1_HUMAN; MAGE D1 antigen; MAGE tumor antigen CCF; MAGE-D1 antigen; Melanoma antigen family D 1; Melanoma associated antigen D1; Melanoma-associated antigen D1; Neurotrophin receptor interacting MAGE homolog; Neurotrophin receptor-interacting MAGE homolog; NRAGE; PP2250. |
| Background | Involved in the apoptotic response after nerve growthfactor (NGF) binding in neuronal cells. Binds NGFR/p75NTR andantagonizes its association with NTRK1/TrkA, inhibits cell cycleprogression, and facilitates NGFR-mediated apoptosis. May act as aregulator of the function of DLX family members. May regulateTP53/p53 transcriptional activity and inhibit cell proliferation.Enhances TP53 phosphorylation and accumulation. May enhanceubiquitin ligase activity of RING-type zinc finger-containing E3ubiquitin-protein ligases. Proposed to act through recruitmentand/or stabilization of the Ubl-conjugating enzyme (E2) at theE3:substrate complex. |
| Application Dilution | |
| WB | =1:500-1000 |
Frequently asked questions
Which applications is MAGED1 Monoclonal Antibody (bsm-51582M) validated for, and at what dilution?
bsm-51582M is validated for WB (WB=1:500-1000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does MAGED1 Monoclonal Antibody (bsm-51582M) react with?
Tested reactivity: Human.
How should bsm-51582M be stored?
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise MAGED1 Monoclonal Antibody (bsm-51582M)?
KLH conjugated synthetic peptide derived from human MAGED1 Immunogen range: 50-200/778.