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TPX2 Monoclonal Antibody

Applications

  • WB

Predicted Reactivity

  • Human
Overview
Catalog # bsm-51631M
Product Name TPX2 Monoclonal Antibody
Applications WB
Predicted Reactivity Human
Specifications
Conjugation Unconjugated
Host Mouse
Source Recombinant human TPX2 between 1-531 amino acids.
Clonality Monoclonal
Clone # C3A12
Concentration 0.5ug/ul
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 22974
Swiss Prot Q9ULW0
Subcellular location Cytoplasm, Nucleus
Synonyms C20ORF1; C20orf2; Chromosome 20 Open Reading Frame 1; Differentially expressed in cancerous and non-cancerous lung cells 2; Differentially expressed in cancerous and noncancerous lung cells 2; Differentially expressed in lung cells 2; Differentially expressed in lung cells; DIL 2; DIL-2; DIL2; FLS353; GD:C20orf1; HCA 519; HCA519; HCTP 4; HCTP4; Hepatocellular carcinoma associated antigen 519; Hepatocellular carcinoma-associated antigen 519; p100; Preferentially expressed in colorectal cancer; Protein FLS353; REPP 86; repp86; Restricted expression proliferation associated protein 100; Restricted expression proliferation-associated protein 100; Targeting protein for XKLP2; TPX 2; TPX2 microtubule associated homolog; TPX2 microtubule associated protein homolog; TPX2_HUMAN.
Background Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
Application Dilution
WB =1:500-2000,