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RAB14 Monoclonal Antibody

Applications

  • WB

Predicted Reactivity

  • Human
  • Mouse
  • Chicken
Overview
Catalog # bsm-51650M
Product Name RAB14 Monoclonal Antibody
Applications WB
Predicted Reactivity Human, Mouse, Chicken
Specifications
Conjugation Unconjugated
Host Mouse
Source Recombinant human RAB14.
Clonality Monoclonal
Clone # A12M1
Concentration 0.5ug/ul
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 51552
Swiss Prot P61106
Subcellular location Cytoplasm
Synonyms F protein binding protein 1; bA165P4.3; FBP; GTPase RAB 14; RAB-14; RAB14 member RAS oncogene family; RAB14_HUMAN; Ras related protein Rab 14; Ras-related protein Rab-14; RP11 165P4.4; Small GTP binding protein RAB14; FBP.
Background Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.
Application Dilution
WB =1:500-2000,