| Overview |
| bsm-51688m |
| RAB7L1 Monoclonal Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Mouse |
| Recombinant human RAB7L1. |
| Monoclonal |
| #REF! |
| IgG1 |
| 0.5ug/ul |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 8934 |
| O14966 |
| Cytoplasm, Cell membrane |
| RAB29; DKFZp686P1051; Rab 7 like protein 1; RAB 7L; Rab7 like protein 1; RAB7 member RAS oncogene family like 1; RAB7L; Ras related protein Rab 7L1; Ras-related protein Rab-7L1; Ras related protein Rab7L1. |
| Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. |
| Application Dilution |
| WB |
=1:500-2000 |
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