DKK2 Monoclonal Antibody
Applications
Predicted Reactivity
Overview | |
Catalog # | bsm-51690M |
Product Name | DKK2 Monoclonal Antibody |
Applications | WB |
Predicted Reactivity | Human, Mouse |
Specifications | |
Conjugation | Unconjugated |
Host | Mouse |
Source | Recombinant human DKK2. |
Clonality | Monoclonal |
Clone # | J3F5 |
Concentration | 0.5ug/ul |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 27123 |
Swiss Prot | Q9UBU2 |
Subcellular location | Secreted |
Synonyms | Dickkopf 2; Dickkopf gene 2; Dickkopf homolog 2; Dickkopf related protein 2; Dickkopf-2; Dickkopf-related protein 2; Dickkopf2; DKK 2; Dkk-2; DKK2_HUMAN; hDkk 2; hDkk-2; hDkk2. |
Background | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
Application Dilution | |
WB | =1:500-1000, |