BMP11 Monoclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-51700m |
| Product Name | BMP11 Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Recombinant protein |
| Predicted Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Recombinant human GDF11. |
| Clonality | Monoclonal |
| Clone # | C4F5 |
| Concentration | Lot Dependent |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 10220 |
| Swiss Prot | O95390 |
| Subcellular location | Cytoplasm, Secreted |
| Synonyms | GDF11; BMP 11; Bone morphogenetic protein 11; GDF 11; Growth differentiation factor 11; Growth/differentiation factor 11; GDF11_HUMAN. |
| Background | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. |
| Application Dilution | |
| WB | =1:500-2000 |
Frequently asked questions
Which applications is BMP11 Monoclonal Antibody (bsm-51700M) validated for, and at what dilution?
bsm-51700M is validated for WB (WB=1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does BMP11 Monoclonal Antibody (bsm-51700M) react with?
Tested reactivity: Recombinant protein. Predicted reactivity (expected from sequence homology but not yet tested): Human.
How should bsm-51700M be stored?
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise BMP11 Monoclonal Antibody (bsm-51700M)?
Recombinant human GDF11.