| Overview |
| bsm-51700M |
| BMP11 Monoclonal Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Mouse |
| Recombinant human GDF11. |
| Monoclonal |
| C4F5 |
| 0.5ug/ul |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 10220 |
| O95390 |
| Cytoplasm, Secreted |
| GDF11; BMP 11; Bone morphogenetic protein 11; GDF 11; Growth differentiation factor 11; Growth/differentiation factor 11; GDF11_HUMAN. |
| Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. |
| Application Dilution |
| WB |
=1:500-2000， |
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