ADAMTS4 Monoclonal Antibody

$Lane 1: Recombinant protein lysates probed with ADAMTS4 Monoclonal Antibody, Unconjugated (bsm-51704M) at 1:8000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.$

Lane 1: Recombinant protein lysates probed with ADAMTS4 Monoclonal Antibody, Unconjugated (bsm-51704M) at 1:8000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.

Applications

Reactivity

Recombinant protein

Predicted Reactivity

Human

Overview
Catalog #	bsm-51704m
Product Name	ADAMTS4 Monoclonal Antibody
Applications	WB
Reactivity	Recombinant protein
Predicted Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	Recombinant human ADAMTS4.
Clonality	Monoclonal
Clone #	D4F8
Concentration	0.5ug/ul
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	9507
Swiss Prot	O75173
Subcellular location	Cell membrane
Synonyms	ATS4_HUMAN; ADAMTS 4; A disintegrin and metalloproteinase with thrombospondin motifs 4; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 4; A disintegrin like and metalloprotease with thrombospondin type 1 motif 4; ADAM metallopeptidase with thrombospondin type 1 motif 4; ADAM TS 4; ADAM TS4; ADAMTS-2; ADAMTS4 protein; ADMP 1; ADMP1; Aggrecanase 1; Aggrecanase1; KIAA0688.
Background	Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu- -Ala-393' site.
Application Dilution
WB	=1:1000-4000