UBE2C Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51705m |
| Product Name | UBE2C Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | KLH conjugated synthetic peptide derived from human UBE2C |
| Immunogen Range | 121-179/179 |
| Clonality | Monoclonal |
| Clone # | H11J9 |
| Concentration | Lot Dependent |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 11065 |
| Swiss Prot | O00762 |
| Subcellular location | Cytoplasm, Nucleus, Cell membrane |
| Synonyms | UBE2C_HUMAN; Cyclin selective ubiquitin carrier protein; dJ447F3.2; Mitotic specific ubiquitin conjugating enzyme; UB E2C; UBCH 10; UBCH10; UBE 2C; Ubiquitin carrier protein C; Ubiquitin carrier protein E2 C; Ubiquitin carrier protein E2C; Ubiquitin conjugating enzyme E2 C; Ubiquitin conjugating enzyme E2C; Ubiquitin protein ligase C; Ubiquitin-conjugating enzyme E2 C; Ubiquitin-protein ligase C. |
| Background | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit. |
| Application Dilution | |
| WB | =1:1000-4000 |
Frequently asked questions
Which applications is UBE2C Monoclonal Antibody (bsm-51705M) validated for, and at what dilution?
bsm-51705M is validated for WB (WB=1:1000-4000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does UBE2C Monoclonal Antibody (bsm-51705M) react with?
Tested reactivity: Human.
How should bsm-51705M be stored?
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise UBE2C Monoclonal Antibody (bsm-51705M)?
KLH conjugated synthetic peptide derived from human UBE2C Immunogen range: 121-179/179.