4E-BP1/2/3 (Thr45) (3G2) Monoclonal Antibody

$Western blot analysis of 4E-BP1\/2\/3 phosphorylation untreated (A), calyculin A treated (B) and calyculin A and lambda protein phosphatase treated (C) Jurkat whole cell lysates.$

Western blot analysis of 4E-BP1\/2\/3 phosphorylation untreated (A), calyculin A treated (B) and calyculin A and lambda protein phosphatase treated (C) Jurkat whole cell lysates.

Applications

Reactivity

Human
Rat

Overview
Catalog #	bsm-52008m
Product Name	4E-BP1/2/3 (Thr45) (3G2) Monoclonal Antibody
Applications	WB
Reactivity	Human, Rat
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	Synthetic peptide derived from human 4E-BP1/2/3 (Thr 45), around 35-55aa.
Modification Site	Thr 45
Clonality	Monoclonal
Clone #	3G2
Isotype	IgG2a
Concentration	Lot Dependent
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	19
Swiss Prot	O95477
Synonyms	ABCA1 phospho S2054; p-ABCA1 phospho S2054; ATP binding cassette transporter A1; ABC 1; ABC Transporter 1; ABC1; ABCA 1; ABCA1; ATP binding Cassette 1; ATP binding cassette sub family A ABC1 member 1; ATP binding cassette sub family A member 1; ATP binding cassette sub-family A member 1; ATP binding Cassette Transporter 1; ATP-binding Cassette 1; ATP-binding Cassette Transporter 1; CERP; Cholesterol Efflux Regulatory Protein; FLJ14958; HDLDT1; Membrane bound; MGC164864; MGC165011; TD; TGD; ABCA1_HUMAN.
Background	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
Application Dilution
WB	1:300-5000