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Cyclin E1 Recombinant Antibody

Applications

  • WB
  • IHC-P
  • IHC-F
  • IF
  • ICC/IF

Reactivity

  • Human
Overview
Catalog # bsm-52048r
Product Name Cyclin E1 Recombinant Antibody
Applications WB, IHC-P, IHC-F, IF, ICC/IF
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic peptide derive from human cyclin e1
Clonality Recombinant
Clone # #REF!
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Storage Condition Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 898
Swiss Prot P24864
Synonyms Cyclin E1 phospho T77; p-Cyclin E1 phospho T77; Cyclin E1 Thr77; CCNE 1; CCNE;CCNE1;Cyclin E1 antibody Cyclin Es;Cyclin Et;CyclinE; G1/S specic cyclin E.
Background Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
Application Dilution
WB IHC-P1:200-400
IHC-P IFICC1:50-200
IHC-F
IF
ICC/IF