Cytokeratin 4 Recombinant Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-52062r-biotin-100uL |
| Product Name | Cytokeratin 4 Recombinant Antibody, Biotin Conjugated |
| Applications |
WB
|
| Reactivity | Rat |
| Predicted Reactivity | Human |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | Recombinant human Cytokeratin 4 protein, around 350-480aa. |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 3851 |
| Swiss Prot | P19013 |
| Synonyms | Keratin, type II cytoskeletal 4; KRT4 |
| Background | Defects in KRT4 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Cytokeratin 4 Recombinant Antibody, Biotin Conjugated (bsm-52062R-Biotin) validated for, and at what dilution?
bsm-52062R-Biotin is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Cytokeratin 4 Recombinant Antibody, Biotin Conjugated (bsm-52062R-Biotin) react with?
Tested reactivity: Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human.
How should bsm-52062R-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Cytokeratin 4 Recombinant Antibody, Biotin Conjugated (bsm-52062R-Biotin)?
Recombinant human Cytokeratin 4 protein, around 350-480aa.
