| Overview |
| bsm-52062r-cy3-100ul |
| Cytokeratin 4 Recombinant Antibody, Cy3 Conjugated |
| WB |
| Rat |
| Human |
| Specifications |
| Cy3 |
| Rabbit |
| Recombinant human Cytokeratin 4 protein, around 350-480aa. |
| Recombinant |
| IgG |
| Lot Dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3851 |
| P19013 |
| Keratin, type II cytoskeletal 4; KRT4 |
| Defects in KRT4 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved. |
| Application Dilution |
| WB |
1:300-5000 |
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