HDAC4 Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52085r-100uL |
| Product Name | HDAC4 Monoclonal Antibody |
| Applications |
WB
ICC/IF
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant human HDAC4 protein, around C-terminal 100aa. |
| Clonality | Monoclonal |
| Clone # | 6B10 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 9759 |
| Swiss Prot | P56524 |
| Synonyms | HDAC4Ser246; HDAC4S246; p-HDAC4Ser246; p-HDAC4S246; HD 4; HD4; HDAC 4; HDAC A; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288; EC 3.5.1.98; HA6116; HDA4_CAEEL; Histone deacetylase 4; CeHDA-7; Histone deacetylase 7. |
| Background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]. |
| Application Dilution | |
| WB | 1:300-5000 |
| ICC/IF | 1:50-100 |
Frequently asked questions
Which applications is HDAC4 Monoclonal Antibody (bsm-52085R) validated for, and at what dilution?
bsm-52085R is validated for WB (1:300-5000); ICC/IF (1:50-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does HDAC4 Monoclonal Antibody (bsm-52085R) react with?
Tested reactivity: Human.
How should bsm-52085R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise HDAC4 Monoclonal Antibody (bsm-52085R)?
Recombinant human HDAC4 protein, around C-terminal 100aa.