STAT2 (4B1) Monoclonal Antibody

$A431 cells were fixed in paraformaldehyde and permeabilized with 0.25% Triton X100\/PBS. Antibody incubation with STAT2 (4B1) Monoclonal Antibody, Unconjugated (bsm-52234R) at 1:100 for 1hr at 37\u00b0C, followed by a conjugated secondary antibody and DAPI for nuclei staining$

A431 cells were fixed in paraformaldehyde and permeabilized with 0.25% Triton X100\/PBS. Antibody incubation with STAT2 (4B1) Monoclonal Antibody, Unconjugated (bsm-52234R) at 1:100 for 1hr at 37\u00b0C, followed by a conjugated secondary antibody and DAPI for nuclei staining

$Paraformaldehyde-fixed and paraffin-embedded Human lung cancer tissue was incubated with STAT2 (4B1) Monoclonal Antibody, Unconjugated (bsm-52234R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counter stained with hematoxylin$

Paraformaldehyde-fixed and paraffin-embedded Human lung cancer tissue was incubated with STAT2 (4B1) Monoclonal Antibody, Unconjugated (bsm-52234R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counter stained with hematoxylin

$Paraformaldehyde-fixed and paraffin-embedded Mouse skin tissue was incubated with STAT2 (4B1) Monoclonal Antibody, Unconjugated (bsm-52234R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin$

Paraformaldehyde-fixed and paraffin-embedded Mouse skin tissue was incubated with STAT2 (4B1) Monoclonal Antibody, Unconjugated (bsm-52234R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin

$Paraformaldehyde-fixed and paraffin-embedded Human colon cancer tissue was incubated with STAT2 (4B1) Monoclonal Antibody, Unconjugated (bsm-52234R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counter stained with hematoxylin$

Paraformaldehyde-fixed and paraffin-embedded Human colon cancer tissue was incubated with STAT2 (4B1) Monoclonal Antibody, Unconjugated (bsm-52234R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counter stained with hematoxylin

Applications

IHC-P
IF(ICC)

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-52234R
Product Name	STAT2 (4B1) Monoclonal Antibody
Applications	IHC-P, IF(ICC)
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant human STAT2 protein, around N-terminal 1-100aa.
Clonality	Monoclonal
Clone #	4B1
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	6773
Swiss Prot	P52630
Synonyms	P113; ISGF-3; STAT113; Signal transducer and activator of transcription 2; STAT2
Background	Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Application Dilution
IHC-P	1:200-400
IF(ICC)	1:50-200

Applications

Reactivity

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