VDAC1 (9A7 ) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IHC
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-52251R
Product Name VDAC1 (9A7 ) Monoclonal Antibody
Applications WB, IHC-P, IHC, IF
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Human VDAC1 protein between 1 to 100 amino acids
Immunogen Range 1-100/283
Clonality Monoclonal
Clone # 9A7
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 7416
Swiss Prot P21796
Synonyms Voltage-dependent anion-selective channel protein 1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC-1, hVDAC1
Background Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC
IF