Filamin A Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52260R-100uL |
| Product Name | Filamin A Recombinant Antibody |
| Applications |
WB
FCM
IHC-P
IF(ICC)
IHC
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Human Filamin A, C-terminus |
| Clonality | Monoclonal |
| Clone # | 2G3 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 2316 |
| Swiss Prot | P21333 |
| Synonyms | Filamin-A, Actin-binding protein 280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin, FLN-A, ABP-280 |
| Background | Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintainance (By similarity). |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
| IHC-P | 1:200-400 |
| IF(ICC) | 1:50-200 |
| IHC | |
Frequently asked questions
Which applications is Filamin A Recombinant Antibody (bsm-52260R) validated for, and at what dilution?
bsm-52260R is validated for WB (1:300-5000); FCM (1:20-100); IHC-P (1:200-400); IF(ICC) (1:50-200); IHC. These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Filamin A Recombinant Antibody (bsm-52260R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-52260R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Filamin A Recombinant Antibody (bsm-52260R)?
Human Filamin A, C-terminus