PUMA (2G6) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52276R |
| Product Name | PUMA (2G6) Monoclonal Antibody |
| Applications |
WB
FCM
IHC-P
IF(ICC)
IHC
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Human PUMA from 150 amino acids to the C-terminus |
| Clonality | Monoclonal |
| Clone # | 2G6 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 27113 |
| Swiss Prot | Q9BXH1 |
| Synonyms | Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, BBC3 |
| Background | Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis (PubMed:11463391). Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis (PubMed:23340338). |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
| IHC-P | 1:200-400 |
| IF(ICC) | 1:50-200 |
| IHC | |