| Overview |
| bsm-52303R |
| Caveolin-1 (9C11) Monoclonal Antibody |
| WB, IHC-P, IF(IHC-P), IF(ICC) |
| Human, Mouse |
| Specifications |
| Unconjugated |
| Rabbit |
| Human Caveolin-1 aa 100-250 |
| Monoclonal |
| #REF! |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20C for 12 months. |
| Target |
| 857 |
| Q03135 |
| Cell membrane, Golgi apparatus |
| Caveolin-1; CAV1; CAV |
| May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IF(IHC-P) |
1:50-200 |
| IF(ICC) |
1:50-200 |