Overview |
bsm-52373r |
MMP14 Recombinant Antibody |
WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Recombinant human MMP14 between 150 to 250 amino acids |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
Target |
4323 |
P50281 |
Matrix metalloproteinase-14, MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP-14, MTMMP1, MT1-MMP, MT1MMP, MT-MMP 1 |
Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |
IP |
1-2ug |
IF |
|
Flow-Cyt |
1ug/Test |
ICC/IF |
1:50-100 |