Apaf-1 (4G2) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52381R |
| Product Name | Apaf-1 (4G2) Monoclonal Antibody |
| Applications |
WB
IHC-P
IF(ICC)
IHC
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant human Apaf-1 between 1 to 300 amino acids |
| Clonality | Monoclonal |
| Clone # | 4G2 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 317 |
| Swiss Prot | O14727 |
| Synonyms | Apoptotic protease-activating factor 1, APAF-1, APAF1 |
| Background | Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| IF(ICC) | 1:50-200 |
| IHC | |