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Estrogen Related Receptor alpha (1H13) Monoclonal Antibody

Flow cytometric analysis of HeLa cells with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).
Flow cytometric analysis of HeLa cells with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).
MCF-7 cell lysate probed with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C
MCF-7 cell lysate probed with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-52495R
Product Name Estrogen Related Receptor alpha (1H13) Monoclonal Antibody
Applications WB, FCM
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein within Human Estrogen Related Receptor alpha aa 1-100
Clonality Monoclonal
Clone # 1H13
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 2101
Swiss Prot P11474
Synonyms Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, Nuclear receptor subfamily 3 group B member 1, ERR-alpha, ESRRA, ERR1, ESRL1, NR3B1
Background Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
Application Dilution
WB 1:300-5000
FCM 1:20-100

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