Estrogen Related Receptor alpha (1H13) Monoclonal Antibody

Flow cytometric analysis of HeLa cells with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).

$MCF-7 cell lysate probed with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C$

MCF-7 cell lysate probed with Estrogen Related Receptor alpha (1H13) Monoclonal Antibody (bsm-52495R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C

Applications

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-52495R
Product Name	Estrogen Related Receptor alpha (1H13) Monoclonal Antibody
Applications	WB, FCM
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant protein within Human Estrogen Related Receptor alpha aa 1-100
Clonality	Monoclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20C for 12 months.
Target
Gene ID	2101
Swiss Prot	P11474
Synonyms	Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, Nuclear receptor subfamily 3 group B member 1, ERR-alpha, ESRRA, ERR1, ESRL1, NR3B1
Background	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
Application Dilution
WB	1:300-5000
FCM	1:20-100