Cyclooxygenase 2 Recombinant Antibody, AbBy Fluor-594 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52502r-bf594 |
| Product Name | Cyclooxygenase 2 Recombinant Antibody, AbBy Fluor-594 Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | AbBy Fluor-594 |
| Host | Rabbit |
| Source | Human COX2/ Cyclooxygenase 2 between 50 to 200 amino acids |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Swiss Prot | P35354 |
| Synonyms | Prostaglandin G/H synthase 2, Cyclooxygenase-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, COX-2, PGH synthase 2, PGHS-2, PTGS2 |
| Background | Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | |
Frequently asked questions
Which applications is Cyclooxygenase 2 Recombinant Antibody, AbBy Fluor-594 Conjugated (bsm-52502R-BF594) validated for, and at what dilution?
bsm-52502R-BF594 is validated for WB (1:300-5000); IF. These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Cyclooxygenase 2 Recombinant Antibody, AbBy Fluor-594 Conjugated (bsm-52502R-BF594) react with?
Tested reactivity: Human, Mouse.
How should bsm-52502R-BF594 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Cyclooxygenase 2 Recombinant Antibody, AbBy Fluor-594 Conjugated (bsm-52502R-BF594)?
Human COX2/ Cyclooxygenase 2 between 50 to 200 amino acids
What are the excitation and emission wavelengths of the AbBy Fluor-594 conjugate (bsm-52502R-BF594)?
AbBy Fluor-594 on bsm-52502R-BF594: excitation / emission 590nm/617nm.