F11R/JAM-A/CD321 Recombinant Antibody, RBITC Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-52561r-rbitc |
| Product Name | F11R/JAM-A/CD321 Recombinant Antibody, RBITC Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat |
| Specifications | |
| Conjugation | RBITC |
| Host | Rabbit |
| Source | Human Junctional Adhesion Molecule 1 between 28-241 amino acids |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 50848 |
| Swiss Prot | Q9Y624 |
| Subcellular location | Cell membrane, Extracellular domain, Cell junction |
| Synonyms | Junctional adhesion molecule A; Junctional adhesion molecule 1; Platelet F11 receptor; Platelet adhesion molecule 1; CD321; JAM-A; JAMA; JAM-1; JAM1; PAM-1; F11R |
| Background | Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. |
| Application Dilution | |
| WB | 1:500-2000 |
Frequently asked questions
Which applications is F11R/JAM-A/CD321 Recombinant Antibody, RBITC Conjugated (bsm-52561R-RBITC) validated for, and at what dilution?
bsm-52561R-RBITC is validated for WB(WB) (1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does F11R/JAM-A/CD321 Recombinant Antibody, RBITC Conjugated (bsm-52561R-RBITC) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat.
How should bsm-52561R-RBITC be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise F11R/JAM-A/CD321 Recombinant Antibody, RBITC Conjugated (bsm-52561R-RBITC)?
Human Junctional Adhesion Molecule 1 between 28-241 amino acids
What are the excitation and emission wavelengths of the RBITC conjugate (bsm-52561R-RBITC)?
RBITC on bsm-52561R-RBITC: excitation / emission 570nm/595nm.