IKB beta (9D10) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52571R |
| Product Name | IKB beta (9D10) Monoclonal Antibody |
| Applications |
WB
IHC-P
IF(ICC)
IHC
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Full length protein |
| Clonality | Monoclonal |
| Clone # | 9D10 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 4793 |
| Swiss Prot | Q15653 |
| Synonyms | NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9, NF-kappa-BIB, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9, TRIP-9, NFKBIB |
| Background | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| IF(ICC) | 1:50-200 |
| IHC | |