| Overview |
| bsm-52576r-pbs-only-100ul |
| MUC1 Recombinant Antibody, PBS Only Conjugated |
| WB, IHC-P, IHC-F, IF(IHC-P), IF(ICC), IP |
| Human, Mouse, Rat |
| Specifications |
| PBS Only |
| Rabbit |
| Human MUC1 between 1-100 amino acids |
| Monoclonal |
| 5G5 |
| IgG |
| Lot Dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 4582 |
| P15941 |
| Mucin-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, PEMT, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin, CD_antigen: CD227, MUC-1, CA 15-3, KL-6, PUM, PEM, EMA, MUC1 |
| The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. |
| Application Dilution |
| WB |
1:1000-5000 |
| IHC-P |
IHC-P1:200-800 |
| IHC-F |
IHC-F1:200-800 |
| IF(IHC-P) |
IFIHC-P1:200-800 |
| IF(ICC) |
IFICC1:100-200 |
| IP |
IP1:20-50 |
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