SHP2 (11B5) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52593R |
| Product Name | SHP2 (11B5) Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | SHP2 between 200 to 550 amino acids |
| Clonality | Monoclonal |
| Clone # | 11B5 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 5781 |
| Swiss Prot | Q06124 |
| Synonyms | Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, PTP-1D, PTP-2C, SHP-2, Shp2, PTPN11 |
| Background | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. |
| Application Dilution | |
| WB | 1:300-5000 |