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Stromal interaction molecule 1 (7C4) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IHC

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-52677R
Product Name Stromal interaction molecule 1 (7C4) Monoclonal Antibody
Applications WB, IHC-P, IHC
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Human Stromal interaction molecule 1 between 1-600 amino acids
Clonality Monoclonal
Clone # 7C4
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 6786
Swiss Prot Q13586
Synonyms Stromal interaction molecule 1, STIM1
Background Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC