Hsp75 (6C2) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52678R-100uL |
| Product Name | Hsp75 (6C2) Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | N terminal human Hsp75 |
| Clonality | Monoclonal |
| Clone # | 6C2 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 10131 |
| Swiss Prot | Q12931 |
| Synonyms | Heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, HSP 75, TRAP-1, TRAP1 |
| Background | Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Hsp75 (6C2) Monoclonal Antibody (bsm-52678R) validated for, and at what dilution?
bsm-52678R is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Hsp75 (6C2) Monoclonal Antibody (bsm-52678R) react with?
Tested reactivity: Human.
How should bsm-52678R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Hsp75 (6C2) Monoclonal Antibody (bsm-52678R)?
N terminal human Hsp75