HDAC8 (2T1) Monoclonal Antibody

Flow cytometric analysis of K562 cells with HDAC8 (2T1) Monoclonal Antibody (bsm-52702R) at 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).

$K562 cell lysate probed with HDAC8 (2T1) Monoclonal Antibody (bsm-52702R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

K562 cell lysate probed with HDAC8 (2T1) Monoclonal Antibody (bsm-52702R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

Applications

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-52702R
Product Name	HDAC8 (2T1) Monoclonal Antibody
Applications	WB, FCM
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant human HDAC8 between 50 to 150 amino acids
Clonality	Monoclonal
Clone #	2T1
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	55869
Swiss Prot	Q9BY41
Synonyms	Histone deacetylase 8, HD8, HDAC8
Background	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
Application Dilution
WB	1:300-5000
FCM	1:20-100

Applications

Reactivity

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