Doublecortin (7C4) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52786R |
| Product Name | Doublecortin (7C4) Monoclonal Antibody |
| Applications |
WB
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Human Doublecortin aa 250 to the C-terminus |
| Clonality | Monoclonal |
| Clone # | 7C4 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 1641 |
| Swiss Prot | O43602 |
| Synonyms | Neuronal migRation protein doublecortin, Doublin, Lissencephalin-X, Lis-X, DCX |
| Background | Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |