MMP13 Recombinant Antibody, AbBy Fluor-750 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-52798r-bf750-100uL |
| Product Name | MMP13 Recombinant Antibody, AbBy Fluor-750 Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Mouse |
| Specifications | |
| Conjugation | AbBy Fluor-750 |
| Host | Rabbit |
| Source | N terminus human MMP13 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 4322 |
| Swiss Prot | P45452 |
| Synonyms | Collagenase 3, Matrix metalloproteinase-13, MMP-13, MMP13 |
| Background | Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion. |
| Application Dilution | |
| WB | 1:500-2000 |
Frequently asked questions
Which applications is MMP13 Recombinant Antibody, AbBy Fluor-750 Conjugated (bsm-52798R-BF750) validated for, and at what dilution?
bsm-52798R-BF750 is validated for WB(WB) (1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does MMP13 Recombinant Antibody, AbBy Fluor-750 Conjugated (bsm-52798R-BF750) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse.
How should bsm-52798R-BF750 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise MMP13 Recombinant Antibody, AbBy Fluor-750 Conjugated (bsm-52798R-BF750)?
N terminus human MMP13
What are the excitation and emission wavelengths of the AbBy Fluor-750 conjugate (bsm-52798R-BF750)?
AbBy Fluor-750 on bsm-52798R-BF750: excitation / emission 749nm/775nm.