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ABCG2 Recombinant Antibody, AbBy Fluor-555 Conjugated

Applications

  • WB
  • IF

Reactivity

  • Human
Overview
Catalog # bsm-52821r-bf555-100uL
Product Name ABCG2 Recombinant Antibody, AbBy Fluor-555 Conjugated
Applications
WB IF
Reactivity Human
Specifications
Conjugation AbBy Fluor-555
Host Rabbit
Source Human ABCG2 aa 1-400
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 9429
Swiss Prot Q9UNQ0
Synonyms ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, URate exporter, CD_antigen: CD338, ABCG2
Background High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
Application Dilution
WB 1:300-5000
IF

Frequently asked questions

Which applications is ABCG2 Recombinant Antibody, AbBy Fluor-555 Conjugated (bsm-52821R-BF555) validated for, and at what dilution?

bsm-52821R-BF555 is validated for WB (1:300-5000); IF. These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does ABCG2 Recombinant Antibody, AbBy Fluor-555 Conjugated (bsm-52821R-BF555) react with?

Tested reactivity: Human.

How should bsm-52821R-BF555 be stored?

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise ABCG2 Recombinant Antibody, AbBy Fluor-555 Conjugated (bsm-52821R-BF555)?

Human ABCG2 aa 1-400

What are the excitation and emission wavelengths of the AbBy Fluor-555 conjugate (bsm-52821R-BF555)?

AbBy Fluor-555 on bsm-52821R-BF555: excitation / emission 553nm/568nm.