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Actin (6C11) Monoclonal Antibody

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat
  • Zebrafish
Overview
Catalog # bsm-52832R
Product Name Actin (6C11) Monoclonal Antibody
Applications WB
Reactivity Human, Mouse, Rat, Zebrafish
Specifications
Conjugation Unconjugated
Host Rabbit
Source Full length protein
Clonality Monoclonal
Clone # 6C11
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 58
Swiss Prot P68133
Synonyms Actin, alpha skeletal muscle, Alpha-actin-1, ACTA1
Background The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
Application Dilution
WB 1:300-5000