CD41/ITGA2B Recombinant Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52912r-biotin-100ul |
| Product Name | CD41/ITGA2B Recombinant Antibody, Biotin Conjugated |
| Applications |
IHC-F
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | A synthesized peptide derived from human Integrin alpha 2b |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 3674 |
| Swiss Prot | P08514 |
| Subcellular location | Cell membrane |
| Synonyms | BDPLT16; BDPLT2; CD41; CD41B; FMAIT2; GP2B; GPIIb; GT; GT1; GTA; HPA3; PPP1R93; alphaIIb; ITA2B_HUMAN; ITGA2B; GPalpha IIb (GPIIb); Platelet membrane glycoprotein IIb; ITGAB; ITA2B_MOUSE; integrin subunit alpha 2b; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B); integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); protein phosphatase 1, regulatory subunit 93; platelet glycoprotein IIb of IIb/IIIa complex; Integrin alpha-IIb |
| Background | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
| Application Dilution | |
| IHC-F | 1:100-500 |
Frequently asked questions
Which applications is CD41/ITGA2B Recombinant Antibody, Biotin Conjugated (bsm-52912R-Biotin) validated for, and at what dilution?
bsm-52912R-Biotin is validated for IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CD41/ITGA2B Recombinant Antibody, Biotin Conjugated (bsm-52912R-Biotin) react with?
Tested reactivity: Human.
How should bsm-52912R-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CD41/ITGA2B Recombinant Antibody, Biotin Conjugated (bsm-52912R-Biotin)?
A synthesized peptide derived from human Integrin alpha 2b