NeuroD1 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52948r-100uL |
| Product Name | NeuroD1 Recombinant Antibody |
| Applications |
WB
|
| Reactivity | Human, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | N terminal human NeuroD1 |
| Immunogen Range | 1-50/356 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 4760 |
| Swiss Prot | Q13562 |
| Subcellular location | Nucleus |
| Synonyms | Neurogenic differentiation factor 1; Class A basic helix-loop-helix protein 3; NeuroD; NeuroD1; bHLHa3; NEUROD1; BETA2; BHF-1; MODY6. |
| Background | Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. |
| Application Dilution | |
| WB | 1:500-2000 |
Frequently asked questions
Which applications is NeuroD1 Recombinant Antibody (bsm-52948R) validated for, and at what dilution?
bsm-52948R is validated for WB(WB) (1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NeuroD1 Recombinant Antibody (bsm-52948R) react with?
Tested reactivity: Human, Rat.
How should bsm-52948R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise NeuroD1 Recombinant Antibody (bsm-52948R)?
N terminal human NeuroD1 Immunogen range: 1-50/356.