ITPR1 (5G10) Monoclonal Antibody

$Paraformaldehyde-fixed and paraffin-embedded Mouse Hippocampus tissue incubated ITPR1 (5G10) Monoclonal Antibody (bsm-54046R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.$

Paraformaldehyde-fixed and paraffin-embedded Mouse Hippocampus tissue incubated ITPR1 (5G10) Monoclonal Antibody (bsm-54046R) at 1:100, overnight at 4\u00b0C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.

Applications

IHC-P

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-54046R
Product Name	ITPR1 (5G10) Monoclonal Antibody
Applications	IHC-P
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Human IP3 receptor aa 1770-1900
Clonality	Monoclonal
Clone #	5G10
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store for 1 year at -20C from date of shipment. Store for 1 year at -20C from date of shipment.
Target
Gene ID	3708
Swiss Prot	Q14643
Synonyms	Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1; IP3 Receptor.
Background	Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Application Dilution
IHC-P	1:200-400

Applications

Reactivity

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