ITPR1 (5G10) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54046R |
| Product Name | ITPR1 (5G10) Monoclonal Antibody |
| Applications |
IHC-P
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Human IP3 receptor aa 1770-1900 |
| Clonality | Monoclonal |
| Clone # | 5G10 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store for 1 year at -20°C from date of shipment. Store for 1 year at -20°C from date of shipment. |
| Target | |
| Gene ID | 3708 |
| Swiss Prot | Q14643 |
| Synonyms | Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1; IP3 Receptor. |
| Background | Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). |
| Application Dilution | |
| IHC-P | 1:200-400 |