Insulin Receptor R (8A1) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54080R |
| Product Name | Insulin Receptor R (8A1) Monoclonal Antibody |
| Applications |
WB
IHC-P
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | N terminal Human Insulin Receptor R |
| Clonality | Monoclonal |
| Clone # | 8A1 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Target | |
| Gene ID | 3645 |
| Swiss Prot | P14616 |
| Synonyms | Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, IRR, INSRR |
| Background | The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |