Overview |
bsm-54080R |
Insulin Receptor R (8A1) Monoclonal Antibody |
WB, IHC-P |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
N terminal Human Insulin Receptor R |
Monoclonal |
8A1 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Target |
3645 |
P14616 |
Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, IRR, INSRR |
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |