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Protein C (4G10) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(IHC-P)
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-54086R
Product Name Protein C (4G10) Monoclonal Antibody
Applications
WB IHC-P IF(IHC-P) IF(ICC)
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Internal sequence of Human Protein C
Clonality Monoclonal
Clone # 4G10
Isotype IgG
Concentration Lot Dependent
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
Gene ID 5624
Swiss Prot P04070
Synonyms Vitamin K-dependent protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide; PROC; THPH3; THPH4
Background Protein C is a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Frequently asked questions

Which applications is Protein C (4G10) Monoclonal Antibody (bsm-54086R) validated for, and at what dilution?

bsm-54086R is validated for WB (1:300-5000); IHC-P (1:200-400); IF(IHC-P) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does Protein C (4G10) Monoclonal Antibody (bsm-54086R) react with?

Tested reactivity: Human.

How should bsm-54086R be stored?

Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise Protein C (4G10) Monoclonal Antibody (bsm-54086R)?

Internal sequence of Human Protein C