Angiopoietin 2 (4G2) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54113R-100uL |
| Product Name | Angiopoietin 2 (4G2) Monoclonal Antibody |
| Applications |
WB
IHC-P
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Human Angiopoietin 2 aa 200-350 |
| Clonality | Monoclonal |
| Clone # | 4G2 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Target | |
| Gene ID | 285 |
| Swiss Prot | O15123 |
| Synonyms | Angiopoietin-2; ANG-2; ANGPT2. |
| Background | Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
Frequently asked questions
Which applications is Angiopoietin 2 (4G2) Monoclonal Antibody (bsm-54113R) validated for, and at what dilution?
bsm-54113R is validated for WB (1:300-5000); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Angiopoietin 2 (4G2) Monoclonal Antibody (bsm-54113R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-54113R be stored?
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Angiopoietin 2 (4G2) Monoclonal Antibody (bsm-54113R)?
Human Angiopoietin 2 aa 200-350