PPARG coactivator 1 beta (6H5) Monoclonal Antibody

$Lane 1: Rat Spleen; Probed with PPARG coactivator 1 beta (6H5) Monoclonal Antibody (bsm-54119R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

Lane 1: Rat Spleen; Probed with PPARG coactivator 1 beta (6H5) Monoclonal Antibody (bsm-54119R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

Flow cytometric analysis of HL-60 cells with PPARG coactivator 1 beta (6H5) Monoclonal Antibody (bsm-54119R) at 1:100 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).

Applications

Reactivity

Human
Rat

Overview
Catalog #	bsm-54119R
Product Name	PPARG coactivator 1 beta (6H5) Monoclonal Antibody
Applications	WB, FCM
Reactivity	Human, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant protein within C-terminal human PGC1 beta
Clonality	Monoclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Target
Gene ID	133522
Swiss Prot	Q86YN6
Subcellular location	Nucleus
Synonyms	Peroxisome proliferator-activated receptor gamma coactivator 1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PPARGC1B; PERC; PGC1; PGC1B; PPARGC1.
Background	Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
Application Dilution
WB	1:300-5000
FCM	1:20-100