| Overview |
| bsm-54119R |
| PPARG coactivator 1 beta (6H5) Monoclonal Antibody |
| WB, FCM |
| Human, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| Recombinant protein within C-terminal human PGC1 beta |
| Monoclonal |
| 6H5 |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
| Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Target |
| 133522 |
| Q86YN6 |
| Nucleus |
| Peroxisome proliferator-activated receptor gamma coactivator 1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PPARGC1B; PERC; PGC1; PGC1B; PPARGC1. |
| Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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