PPARG coactivator 1 beta (6H5) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54119R-100uL |
| Product Name | PPARG coactivator 1 beta (6H5) Monoclonal Antibody |
| Applications |
WB
FCM
|
| Reactivity | Human, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant protein within C-terminal human PGC1 beta |
| Clonality | Monoclonal |
| Clone # | 6H5 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Target | |
| Gene ID | 133522 |
| Swiss Prot | Q86YN6 |
| Subcellular location | Nucleus |
| Synonyms | Peroxisome proliferator-activated receptor gamma coactivator 1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PPARGC1B; PERC; PGC1; PGC1B; PPARGC1. |
| Background | Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is PPARG coactivator 1 beta (6H5) Monoclonal Antibody (bsm-54119R) validated for, and at what dilution?
bsm-54119R is validated for WB (1:300-5000); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does PPARG coactivator 1 beta (6H5) Monoclonal Antibody (bsm-54119R) react with?
Tested reactivity: Human, Rat.
How should bsm-54119R be stored?
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise PPARG coactivator 1 beta (6H5) Monoclonal Antibody (bsm-54119R)?
Recombinant protein within C-terminal human PGC1 beta