GAB1 Recombinant Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-54220r-100uL |
| Product Name | GAB1 Recombinant Antibody |
| Applications |
WB
ICC/IF
|
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant human GAB1 |
| Clonality | Recombinant |
| Clone # | 9B1 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 2549 |
| Swiss Prot | Q13480 |
| Subcellular location | Cytoplasm |
| Synonyms | DFNB26; GAB1_HUMAN; GAB1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1; GAB1_MOUSE; GRB2 associated binding protein 1; deafness, autosomal recessive 26 |
| Background | GAB1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway. |
| Application Dilution | |
| WB | 1:500-2000 |
| ICC/IF | 1:100-200 |
Frequently asked questions
Which applications is GAB1 Recombinant Antibody (bsm-54220R) validated for, and at what dilution?
bsm-54220R is validated for WB (1:500-2000); ICC/IF (1:100-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does GAB1 Recombinant Antibody (bsm-54220R) react with?
Tested reactivity: Human, Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Mouse, Rat.
How should bsm-54220R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GAB1 Recombinant Antibody (bsm-54220R)?
Recombinant human GAB1