GAB1 Recombinant Antibody, APC Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-54220r-apc-100ul |
| Product Name | GAB1 Recombinant Antibody, APC Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | Recombinant human GAB1 |
| Clonality | Recombinant |
| Clone # | 9B1 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2549 |
| Swiss Prot | Q13480 |
| Subcellular location | Cytoplasm |
| Synonyms | DFNB26; GAB1_HUMAN; GAB1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1; GAB1_MOUSE; GRB2 associated binding protein 1; deafness, autosomal recessive 26 |
| Background | GAB1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway. |
| Application Dilution | |
| WB | 1:500-2000 |