STIP1 (2H5) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54308R-100uL |
| Product Name | STIP1 (2H5) Monoclonal Antibody |
| Applications |
WB
IHC-P
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant protein orresponding to human STIP1 aa 1-150 |
| Clonality | Monoclonal |
| Clone # | 2H5 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Target | |
| Gene ID | 10963 |
| Swiss Prot | P31948 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Stress-induced-phosphoprotein 1; Hsc70/Hsp90-organizing protein; Renal carcinoma antigen NY-REN-11; Transformation-sensitive protein IEF SSP 3521; STI1; Hop; STIP1 |
| Background | Stress-induced-phosphoprotein 1 (STI1) functions as a co-chaperone for HSP70 and HSP90 during heat shock response. STI1 exists as either a monomer or a dimer, and this conformational flexibility facilitates its function in organizing HSP70/HSP90. HSP90 acts as an ATPase, and requires the recruitment of client proteins and proper conformation to function. STI1 acts as a "scaffold" for client protein recruitment to the relaxed, ADP-bound conformation of HSP90, thus suppressing ATP turnover during the loading phase and allowing proper function. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is STIP1 (2H5) Monoclonal Antibody (bsm-54308R) validated for, and at what dilution?
bsm-54308R is validated for WB (1:300-5000); IHC-P (1:200-400); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does STIP1 (2H5) Monoclonal Antibody (bsm-54308R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-54308R be stored?
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise STIP1 (2H5) Monoclonal Antibody (bsm-54308R)?
Recombinant protein orresponding to human STIP1 aa 1-150