Oct-1 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54365R |
| Product Name | Oct-1 Recombinant Antibody |
| Applications |
WB
IHC-P
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant protein within human POU2F1 aa 1-150. |
| Clonality | Monoclonal |
| Clone # | 1C14 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Target | |
| Gene ID | 5451 |
| Swiss Prot | P14859 |
| Subcellular location | Nucleus |
| Synonyms | POU domain class 2 transcription factor 1; NF-A1; Octamer-binding protein 1; Octamer-binding transcription factor 1; Oct-1; OTF-1; POU2F1; OCT1; OTF1 |
| Background | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |