NCF2 (3A1) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54404R-100uL |
| Product Name | NCF2 (3A1) Monoclonal Antibody |
| Applications |
WB
IP
IHC-P
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant protein within Human NCF2 aa 150-300. |
| Clonality | Monoclonal |
| Clone # | 3A1 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 4688 |
| Swiss Prot | P19878 |
| Subcellular location | Cytoplasm |
| Synonyms | Neutrophil cytosol factor 2; 67 kDa neutrophil oxidase factor; NADPH oxidase activator 2; Neutrophil NADPH oxidase factor 2; p67-phox; NCF-2; NCF2; NOXA2; P67PHOX |
| Background | Neutrophil cytosolic factor 2, is the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). |
| Application Dilution | |
| WB | 1:300-5000 |
| IP | 1-2ug |
| IHC-P | 1:200-400 |
Frequently asked questions
Which applications is NCF2 (3A1) Monoclonal Antibody (bsm-54404R) validated for, and at what dilution?
bsm-54404R is validated for WB (1:300-5000); IP (1-2ug); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NCF2 (3A1) Monoclonal Antibody (bsm-54404R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-54404R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise NCF2 (3A1) Monoclonal Antibody (bsm-54404R)?
Recombinant protein within Human NCF2 aa 150-300.