Overview |
bsm-54508R |
Phospho-IRF3(S386) Monoclonal Antibody |
WB, IF(ICC) |
Human |
Specifications |
Unconjugated |
Rabbit |
Synthetic phospho-Peptide corresponding to residues surrounding Ser386 of human IRF3. |
Ser386 |
Monoclonal |
6H4 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
3661 |
Q14653 |
Cytoplasm, Nucleus |
IIAE7 antibody, Interferon regulatory factor 3 antibody, IRF 3 antibody, IRF-3 antibody, IRF3 antibody, IRF3_HUMAN antibody, MGC94729 antibody |
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |