Phospho-IRF3(S386) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54508R-100uL |
| Product Name | Phospho-IRF3(S386) Monoclonal Antibody |
| Applications |
WB
IF(ICC)
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Synthetic phospho-Peptide corresponding to residues surrounding Ser386 of human IRF3. |
| Modification Site | Ser386 |
| Clonality | Monoclonal |
| Clone # | 6H4 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 3661 |
| Swiss Prot | Q14653 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | IIAE7 antibody, Interferon regulatory factor 3 antibody, IRF 3 antibody, IRF-3 antibody, IRF3 antibody, IRF3_HUMAN antibody, MGC94729 antibody |
| Background | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is Phospho-IRF3(S386) Monoclonal Antibody (bsm-54508R) validated for, and at what dilution?
bsm-54508R is validated for WB (1:300-5000); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Phospho-IRF3(S386) Monoclonal Antibody (bsm-54508R) react with?
Tested reactivity: Human.
How should bsm-54508R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Phospho-IRF3(S386) Monoclonal Antibody (bsm-54508R)?
Synthetic phospho-Peptide corresponding to residues surrounding Ser386 of human IRF3.