Phospho-Src(Y419) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54519R-100uL |
| Product Name | Phospho-Src(Y419) Monoclonal Antibody |
| Applications |
WB
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Synthetic phospho-Peptide corresponding to residues surrounding Tyr419 of human Src. |
| Modification Site | Tyr419 |
| Clonality | Monoclonal |
| Clone # | 8C13 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 6714 |
| Swiss Prot | P12931 |
| Subcellular location | Cytoplasm, Nucleus, Cell membrane, Mitochondrion inner membrane |
| Synonyms | ASV antibody, Avian sarcoma virus antibody, c SRC antibody, CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody, cSrc antibody, EC 2.7.10.2 antibody, Neuronal CSRC tyrosine specific protein kinase antibody, Neuronal SRC antibody, Oncogene SRC antibody, OTTHUMP00000174476 antibody, OTTHUMP00000174477 antibody, p60 Src antibody, p60-Src antibody, p60Src antibody, pp60c src antibody, pp60c-src antibody, pp60csrc antibody, Proto oncogene tyrosine protein kinase Src antibody, Proto-oncogene c-Src antibody, Proto-oncogene tyrosine-protein kinase Src antibody, Protooncogene SRC antibody, Protooncogene SRC Rous sarcoma antibody, Src antibody, SRC Oncogene antibody, SRC proto oncogene non receptor tyrosine kinase antibody, SRC_HUMAN antibody, SRC1 antibody, Tyrosine kinase pp60c src antibody, Tyrosine protein kinase SRC 1 antibody, Tyrosine protein kinase SRC1 antibody, v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody, V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) antibody, v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian antibody |
| Background | This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is Phospho-Src(Y419) Monoclonal Antibody (bsm-54519R) validated for, and at what dilution?
bsm-54519R is validated for WB (1:300-5000); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Phospho-Src(Y419) Monoclonal Antibody (bsm-54519R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-54519R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Phospho-Src(Y419) Monoclonal Antibody (bsm-54519R)?
Synthetic phospho-Peptide corresponding to residues surrounding Tyr419 of human Src.