HIF-1 beta Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54534R-100uL |
| Product Name | HIF-1 beta Monoclonal Antibody |
| Applications |
WB
IHC
IHC-P
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant protein |
| Clonality | Monoclonal |
| Clone # | 11H1 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 405 |
| Swiss Prot | P27540 |
| Subcellular location | Nucleus |
| Synonyms | arnT antibody, ARNT protein antibody, ARNT_HUMAN antibody, Aryl hydrocarbon receptor nuclear translocator antibody, bHLHe2 antibody, Class E basic helix-loop-helix protein 2 antibody, Dioxin receptor antibody, Dioxin receptor nuclear translocator antibody, Drnt antibody, HIF 1 beta antibody, HIF 1beta antibody, HIF-1-beta antibody, HIF1-beta antibody, HIF1B antibody, HIF1beta antibody, Hypoxia Inducible Factor 1 antibody, Hypoxia inducible factor 1 beta antibody, Hypoxia-inducible factor 1-beta antibody, nuclear translocator antibody, Tango antibody |
| Background | This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC | 1:50-200 |
| IHC-P | 1:200-400 |
Frequently asked questions
Which applications is HIF-1 beta Monoclonal Antibody (bsm-54534R) validated for, and at what dilution?
bsm-54534R is validated for WB (1:300-5000); IHC (1:50-200); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does HIF-1 beta Monoclonal Antibody (bsm-54534R) react with?
Tested reactivity: Human.
How should bsm-54534R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise HIF-1 beta Monoclonal Antibody (bsm-54534R)?
Recombinant protein