Erk1(pT202/pY204)+Erk2(pT185/pY187) Monoclonal Antibody

Applications

  • WB
  • IP

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-54539R
Product Name Erk1(pT202/pY204)+Erk2(pT185/pY187) Monoclonal Antibody
Applications WB, IP
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein
Clonality Monoclonal
Clone # 8B1
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 5595
Swiss Prot P27361
Subcellular location Cytoplasm, Nucleus
Synonyms ,
Background The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].
Application Dilution
WB 1:300-5000
IP 1-2ug